The effects of obesity and how to lose weight
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The effects of obesity and how to lose weight

October 23, 2019

The simple answer is YES, there are about
2.8 million adults per year that die from being overweight or obese globally. Indeed
being overweight and obese is the fifth risk for global death. Most of this burden really
comes from the diabetes that’s out there, from ischemic heart disease associated with
being overweight and obese, and of course, increased risk of cancer associated with being
obese. There is a study called the Framingham Heart
Study, and this shows that if you are obese and a non-smoker, women lose seven years of
life and men lose about six years of life, but if you’re obese and a smoker, both women
and men lose at least 13 years of life. That’s quite significant. Obesity can virtually affect every organ of your body. We can try and look at the complications
of obesity by splitting them up into three sections—metabolic, mechanical, and mental.
If we start with the metabolic complications first, obesity is associated of course with
a very high risk of type II diabetes which leads to a real disease burden. Obesity increases
your risk of cardiovascular disease, including coronary artery disease, the risk of strokes,
the risk of heart attacks, dyslipidemia—that’s abnormalities with cholesterol, and increased
risk of heart failure. Obesity is associated with an increased risk
of gallstones, fatty liver, which can progress to fibrosis and cirrhosis, and of course,
it may then lead to the need for liver transplants. Currently, alcoholic liver disease is the
major cause for liver transplants, but obesity, fatty liver disease and progression of that
is said to be probably the most common cause for a liver transplant in the years to come.
Obesity also affects respiratory disease. We see increased rates of obstructive sleep
apnoea in our patient population and also exacerbation of asthma.
Moving to other metabolic problems, of course the increased risk of cancer is also increased
in our population. This increases risk of cancers such as breast cancers, colorectal, endometrial, ovarian, pancreatic cancers, amongst many others. If we then move on to the mechanical complications of obesity, of course, we know that an increased weight is associated with problems with lower back pain and osteoarthritis. Finally, thinking about mental disease which of course is a really, really important part
of this triad of complications, we know that many of our patients with obesity have depression
and anxiety. Of course, this burden of disease really needs to be tackled and sometimes it’s
very much ignored when we manage our patients. There are many options available for weight
loss but the cornerstone of all these options, of course, is lifestyle interventions, so dietary changes
and increased exercise within our lifestyles. For some patients, lifestyle alone is not
enough and then we have to look to other options, including pharmacotherapy and bariatric surgery.
Pharmacotherapy can be very useful in achieving weight loss and we do have a variety of agents
that we can choose from. Some of these mimic some of our natural hormones, our satiety
hormones that speak to our brain to say that we are full. These interventions can be effective
in achieving and maintaining weight loss. Moving on from pharmacotherapy, there are
some endoscopic options such as the gastric balloon and the EndoBarrier which are endoscopically
placed into our gut. Again, these have been found to be useful in achieving weight loss
and maintaining weight loss although these procedures are temporary and once the device is removed, then the satiety signal is removed and not sustained. Finally, we have bariatric surgery, which has been shown to be an effective way to both
lose weight and maintain weight with time, with studies showing maintained weight loss
up to 20 years and beyond. The three most common procedures worldwide
are the gastric band, the sleeve gastrectomy, and the Roux-En-Y gastric bypass. These procedures
will require lifelong follow-up, especially nutritional supplementation lifelong, and
it is very important that if patients are considering bariatric surgery, which of course
has been shown to be very successful in remission of many of the comorbidities that I’ve spoken
about so far, that they are assessed by an obesity physician to discuss the pros and
cons of surgery and whether it is suitable for them. Our bodies are designed in such a way as to
preserve energy and defend us from times of famine. When we lose weight through a diet,
for example, our gut hormones change in such a way as to increase our hunger hormones
– that’s ghrelin — and to decrease our satiety hormones, and on balance making us feel more hungry. What’s really interesting is that even one
year after we finish our diet, our gut hormones still remember that we’ve lost calories
and the hunger hormones remain high and the satiety hormones remain low; that is, they
haven’t gone back to baseline. Not only that, our basal metabolic rate after weight loss
is lower; that is, the energy required for all our metabolic processes is less than it
used to be. So, on balance, when we lose weight because of the changes in the gut hormones
and the fact that we require less calories to maintain our basal metabolic processes
means that it’s that much harder to keep that weight loss off, in time.

Only registered users can comment.

  1. Big Food and Big Pharma have to keep people obese and sick to make big profits and the NHS with corrupt Senior civil servants, Corrupt, corrupt MPs are shills and colluding with big food and big pharma.

    The wrong food to eat they are pushing will make and keep people obese and make them sick.
    The NHS terrible nutrition advice is proof of this.


    "base meals on starchy foods like potatoes, bread, rice or pasta"

    "Aim to eat at least 2 portions of fish a week, including 1 portion of oily fish."

    "have some dairy or dairy alternatives (such as soya drinks)."

    "Having a sliced banana with your "morning cereal" is an easy way to get 1 portion".

    " Eating a lot of saturated fat can raise cholesterol levels in the blood, and having high cholesterolraises your risk of heart disease".

    A few excerpts from the NHS website…GASP!

    For the truth on optimum human health read the book called the Obesity Code by Dr Jason Fung.

    Youtube Cole Robinson Snake Juice too for a man who walks the walk.

    Share this with your family and friends…it may literally save their life.

  2. Why would a "certified nutritionist with a master's or doctor's or whatev degree' have an obsese millionaire son? BECAUSE EVEN DOCTORS OR FOLKS WITH DOCTOR'S DEGREE ABUSE THEIR CHILDREN?

  3. I am obese and 40. My blood work is impeccable and I have zero health issues. I gave birth naturally to two healthy children while obese. I have an active job and I eat pretty healthy….I just eat too much and enjoy my food. I am dairy and grain free for the past two years and it did nothing for my weight. I am putting this out there to assure people that not all obese people are eating fast food 24/7. I eat fast food maybe once a month if that.

  4. Well , all I have to do is listen to this video once a day , and I will lose weight for sure !!!

  5. here is unlocked secrets that miraculously melted away over 110 pounds of my body to save my own life here are the natural and safe procedures to burn fat in few days please visit here

  6. “It is simply no longer possible to believe much of the clinical research that is published, or to rely on the judgment of trusted physicians or authoritative medical guidelines. I take no pleasure in this conclusion, which I reached slowly and reluctantly over my two decades as an editor of The New England Journal of Medicine. Inaugural female Editor In Chief Marcia Angell.
    “The case against science is straightforward: much of the scientific literature, perhaps half, may simply be untrue. Afflicted by studies with small sample sizes, tiny effects, invalid exploratory analyses, and flagrant conflicts of interest, together with an obsession for pursuing fashionable trends of dubious importance, science has taken a turn towards darkness.” — Richard Horton MD, Editor-in-chief of The Lancet
    Modern medicine is largely quackery based upon fraudulently reported data. To lose weight…eat lots veggies and fruits (no nuts or high fat foods), drink lots of water and get off your back side and move -three times/day. Listening to this Doc made me physically sick – giving advice when they are not even trained in well-being or indeed nutrition to any depth.
    Listen to this lady if you wish to get type 2 diabetes (which is 100% curable through diet), heart disease (100% curable and reversible through diet) and probably cancer (again, curable and reversible through diet).

  7. The best way to lost weight is drinking lots of water before eating anythings it good for health plus clear a'd clean complexion

  8. This is all true so it wont go down well with the fat acceptance movement which is only about fee-fees

  9. The objectivity of scientists is a myth. The simple-minded pursuit of truth is as far from the minds of scientists than ever before. Scientists have vested interests in the next research grant, promotion or publicity inextricably linked with their professional success. They may wish to attack those who do not agree with their mode of thought. And they may promote degenerate colleagues who go along with the facade as to ensure they make their living in ways pleasant to them. This, of course, makes those scientists engaged in research able to make a case for their ism of science where no case exists. This will lead to fatal errors listening or even remotely believing said scientists. For example World renowned expert Professor Bob was quoted “Our research shows this medicine is effective and safe”. 10 years later – over 600,000 people in the EU alone are known to have died after taking the medicine. Bob collects his pension and lives happily ever after. Sadly, this is a real case. That’s twice as many military deaths in the Vietnam War and no penalty. It’s incredulous. Check Vioxx. The science façade is accelerating.

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